When his newfound friend, resourceful watch cat Chloe, begs him to turn her into a human girl, Unico finds his act of kindness having unforeseen consequence as he unwittingly awakens Venus and her minion, who want to destroy them both.

After Unico angers the evil goddess Venus, the brave young unicorn is banished -- and all his memories erased. rescued by the kindhearted West Wind, Unico awakens in an unfamiliar world, where he's befirended by Chloe, an abandoned watch cat. Chloe begs Unico to turn her into a human so she can fend for herself. But that act of kindness has unforseen consequences: Venus and her cutthroat henchma Byron seek to destroy them both! Time is running out for Unico to regain his memories and discover his hidden powers. If he does, then Unico may become one of the most powerful beings in the universe.